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Bibliografía e información
Distribuidor Autorizado de Enzacta - Propietario de Negocio Independiente
Descripción
Alfa PXP Forte
He creado esta página con referencias sobre el ingrediente, los componentes, la forma de acción y las tecnologías con las que han sido elaborados los productos de Enzacta. Igualmente estas referencias son el resultado de mis investigaciones, por lo que yo soy responsable de su compilación y publicación. Por razones de espacio no publico todas las referencias, solo las más representativas.

Esta página está orientada principalmente a los profesionales de la salud (médicos, enfermeras, terapeutas, etc.) cuya respetable formación es objetiva y se fundamenta en hechos comprobados e investigaciones científicas. Así podrán corroborar los efectos benéficos de los productos de Enzacta; gracias a estas referencias podrán estar seguros de ofrecer a sus pacientes una alternativa segura y como un apoyo al tratamiento farmacológico. A mi equipo de trabajo se han integrado médicos y trabajadores de la salud, no solo por la capacitación presencial que he impartido, también por la seriedad y objetividad de estas mis investigaciones y el éxito que tenemos en ayudar a las personas a mejorar su calidad de vida.

De nuevo, si usted es un profesional de la salud y le interesa distribuir estos productos, contácteme y con mucho gusto le ayudaré.

La mayoría de estas referencias fueron consultadas del sitio PubMed Central
http://www.ncbi.nlm.nih.gov/ el archivo gratuito digital de literatura biomédica y de ciencias de la vida, dependiente del Instituto Nacional de Salud (NIH) de los Estados Unidos. Usted puede buscar y comprobar más referencias escribiendo en el buscador el tema; por ejemplo, "humic acid", "DHA", "schizandra chinensis", "purple rice", etc. Como siempre, mi trabajo de investigación consiste en estudiar, discernir y seleccionar los estudios.
Alfa PXP Forte - Alfa PXP Royale - Alfa HFI - Alfa Energy - Alfa B12 - Alfa DHA - Alfa Yakunaah - Undew Suero facial
Alfa DHA
Alfa B12
Alfa Energy
Alfa HFI
Alfa PXP Royale
Alfa Yakunaah
Consulte a su médico.
Este producto no es un medicamento.
El consumo de este producto es responsabilidad de quien lo recomienda y de quien lo toma.
Estas recomendaciones no pretenden suplir a ninguna prescripción o diagnóstico médico ni están orientadas a curar ninguna enfermedad. No se dan consultas médicas.
Estas declaraciones no han sido aprobadas por la FDA.
Si su médico no conoce este producto, invítelo a conocer esta página y a que se contacte conmigo para resolver sus dudas.
La información aquí presentada es resultado de mi investigación y compilaciones de literatura proporcionada por la empresa, además del material de capacitación y cursos presenciales de información de los productos.
De los adaptógenos en general
A Panossian, G Wikman. Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress-Protective Activity.  Pharmaceuticals 2010 , 3 (1), 188-224 Artículo original
Seely D, Singh R. Adaptogenic potential of a polyherbal natural health product: report on a longitudinal clinical trial. Evid Based Complement Alternat Med.  2007 Sep;4(3):375-80. Artículo original
Bacon CG, Mittleman MA, Kawachi I, Giovannucci E, Glasser DB, Rimm EB: A prospective study of risk factors for erectile dysfunction. J Urol. 2006 Jul; 176(1):217-21
Alok C Bharti and Bharat B Aggarwal: Nuclear factor-kappa B and cancer: its role in prevention and therapy.. Biochem Pharmacol. 2002; 64(5-6):883--8
Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity. Panossian A, Wikman G. Curr Clin Pharmacol. 2009 Sep;4(3):198-219. Epub 2009 Sep 1. Review.PMID: 19500070
J Affect Disord. 2010 Jun 24. [Epub ahead of print]PMID: 20579741
Brekhman II, Dardymov IV: New substances of plant origin which increase nonspecific resistance. Annu Rev Pharmacol. 1969; 9:419-30
Robert Bud and Philip Gummett: War, Hot Science: Applied Research in Britain's Defence Laboratories, 1945-1990. . 2002
P J Cooper and M L Barreto and L C Rodrigues: Human allergy and geohelminth infections: a review of the literature and a proposed conceptual model to guide the investigation of possible causal associations.. Br Med Bull. 2006; 79-80:203--18

Rhodiola Rosea
Metabolic profiling of Rhodiola rosea rhizomes by (1)H NMR spectroscopy.Ioset KN, Nyberg NT, Van Diermen D, Malnoe P, Hostettmann K, Shikov AN, Jaroszewski JW. Phytochem Anal. 2010 Sep 16. [Epub ahead of print]PMID: 20848394
Effect of salidroside, active principle of Rhodiola rosea extract, on binge eating. Cifani C, Micioni Db MV, Vitale G, Ruggieri V, Ciccocioppo R, Massi M. Physiol Behav. 2010 Sep 16. [Epub ahead of print]PMID: 20837037
Rhodiola-induced inhibition of adipogenesis involves antioxidant enzyme response associated with pentose phosphate pathway. Lee OH, Kwon YI, Apostolidis E, Shetty K, Kim YC. Phytother Res. 2010 Jul 9. [Epub ahead of print]PMID: 20623718
Neuroprotective effects of salidroside against beta-amyloid-induced oxidative stress in SH-SY5Y human neuroblastoma cells. Zhang L, Yu H, Zhao X, Lin X, Tan C, Cao G, Wang Z.Neurochem Int. 2010 Nov;57(5):547-55. Epub 2010 Jul 6.PMID: 20615444
Second-tier natural antidepressants: Review and critique. Iovieno N, Dalton ED, Fava M, Mischoulon D. J Affect Disord. 2010 Jun 24. [Epub ahead of print]PMID: 20579741
Salidroside induces cell-cycle arrest and apoptosis in human breast cancer cells. Hu X, Zhang X, Qiu S, Yu D, Lin S. Biochem Biophys Res Commun. 2010 Jul 16;398(1):62-7. Epub 2010 Jun 10.PMID: 20541529
Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy. Panossian A, Wikman G, Sarris J. Phytomedicine. 2010 Jun;17(7):481-93. Epub 2010 Apr 7. Review.PMID: 20378318
Double-blind, placebo-controlled, randomised study of single dose effects of ADAPT-232 on cognitive functions. Aslanyan G, Amroyan E, Gabrielyan E, Nylander M, Wikman G, Panossian A. Phytomedicine. 2010 Jun;17(7):494-9. Epub 2010 Apr 5.PMID: 20374974
Effects of chronic Rhodiola Rosea supplementation on sport performance and antioxidant capacity in trained male: preliminary results. Parisi A, Tranchita E, Duranti G, Ciminelli E, Quaranta F, Ceci R, Cerulli C, Borrione P, Sabatini S. J Sports Med Phys Fitness. 2010 Mar;50(1):57-63.PMID: 20308973
Rhodiola rosea ability to enrich cellular antioxidant defences of cultured human keratinocytes. Calcabrini C, De Bellis R, Mancini U, Cucchiarini L, Potenza L, De Sanctis R, Patrone V, Scesa C, Dachà M. Arch Dermatol Res. 2010 Apr;302(3):191-200. Epub 2009 Aug 25.PMID: 19705137
Chronic Rhodiola rosea extract supplementation enforces exhaustive swimming tolerance. Lee FT, Kuo TY, Liou SY, Chien CT. Am J Chin Med. 2009;37(3):557-72.PMID: 19606515
Anti-inflammatory activity of Rhodiola rosea--"a second-generation adaptogen". Pooja, Bawa AS, Khanum F. Phytother Res. 2009 Aug;23(8):1099-102.PMID: 19152369
Rhodiola: a promising anti-aging Chinese herb. Jafari M, Felgner JS, Bussel II, Hutchili T, Khodayari B, Rose MR, Vince-Cruz C, Mueller LD. Rejuvenation Res. 2007 Dec;10(4):587-602.PMID: 17990971
Efficacy and tolerability of a Rhodiola rosea extract in adults with physical and cognitive deficiencies. Fintelmann V, Gruenwald J. Adv Ther. 2007 Jul-Aug;24(4):929-39.PMID: 17901042

Rhaponticum carthamoides
Chemistry and pharmacology of Rhaponticum carthamoides: a review. Kokoska L, Janovska D. Phytochemistry. 2009 May;70(7):842-55. Epub 2009 May 18. Review.PMID: 19457517
Effect of Rhaponticum carthamoides extract on structural and metabolic parameters of erythrocytes in rats with cerebral ischemia. Plotnikov MB, Aliev OI, Vasil'ev AS, Andreeva VY, Krasnov EA, Kalinkina GI. Bull Exp Biol Med. 2008 Jul;146(1):45-8.PMID: 19145347
[Using some new technologies in medical rehabilitation in chronic prostatitis] Korzhachkina NB, Li AA, Kotenko KV. Vopr Kurortol Fizioter Lech Fiz Kult. 2007 Nov-Dec;(6):34-42. Russian. No abstract available. PMID: 18277406
[Cerebroprotector activity of Rhaponticum carthamoides extract in rats with brain ischemia] Plotnikov MB, Logvinov SV, Pugachenko NV, Maslov MIu, Aliev OI, Vasil'ev AS, Suslov NI, Potapov AV. Eksp Klin Farmakol. 2005 Jul-Aug;68(4):19-23. Russian. PMID: 16193651
Screening of some Siberian medicinal plants for antimicrobial activity. Kokoska L, Polesny Z, Rada V, Nepovim A, Vanek T. J Ethnopharmacol. 2002 Sep;82(1):51-3.PMID: 12169406
[The results of experimental study of phytoecdysteroids as erythropoiesis stimulators in laboratory animals] Syrov VN, Nasyrova SS, Khushbaktova ZA. Eksp Klin Farmakol. 1997 May-Jun;60(3):41-4. Russian. PMID: 9324397
Effects of extract from Rhapontcum carthamoides (Willd) Iljin (Leuzea) on learning and memory in rats. Mosharrof AH. Acta Physiol Pharmacol Bulg. 1987;13(3):37-42. Erratum in: Acta Physiol Pharmacol Bulg 1987;13(4):70. PMID: 3439473
[Chemische Analyse der Wurzelextrakte von Rhaponticum carthamoides.] Varga E, Szendrei K, Reisch J. Planta Med. 1982 Jul;45(7):147-148. German. No abstract available. PMID: 17396850
Pharmacological investigations on Rhaponticum carthamoides. Petkov V, Roussinov K, Todorov S, Lazarova M, Yonkov D, Draganova S. Planta Med. 1984 Jun;50(3):205-9. No abstract available. PMID: 6484028
PREPARATIONS WITH STIMULATING EFFECT FROM THE ROOTS OF RHAPONTICUM CARTHAMOIDES (WILLD) ILJIN CULTIVATED IN BULGARIA.] JANKULOW J, ISSAEW I, BOJADJIEWA M, PETKOW W, OWTSCHAROW R. Pharmazie. 1964 May;19:345-7. German. No abstract available. PMID: 14245970

Aralia mandshurica
Antiarrhythmic activity of phytoadaptogens in short-term ischemia-reperfusion of the heart and postinfarction cardiosclerosis. Maslov LN, Lishmanov YB, Arbuzov AG, Krylatov AV, Budankova EV, Konkovskaya YN, Burkova VN, Severova EA. Bull Exp Biol Med. 2009 Mar;147(3):331-4.PMID: 19529855
Effects of Aralia mandshurica and Engelhardtia chrysolepis extracts on some parameters of lipid metabolism in women with nondiabetic obesity. Abidov MT, del Rio MJ, Ramazanov TZ, Klimenov AL, Dzhamirze Sh, Kalyuzhin OV. Bull Exp Biol Med. 2006 Mar;141(3):343-6.PMID: 17073156
[Immunologische Eigenschaften der Saponosidfraktion aus Aralia mandshurica.] Lutomski J, Gorecki P, Ha?asa J. Planta Med. 1981 Jun;42(6):116-117. German. No abstract available. PMID: 17401908
[Determination of the sum of aralosides A, B, C in the roots of Aralia mandshurica] Mal'chukovskii LB, Takhtobaeva GM, Kopylova IE, Libizov NI. Farmatsiia. 1972 Nov-Dec;21(6):45-7. Russian. No abstract available. PMID: 4657595
[PHARMACOGNOSTICAL STUDIES ON THE CHINESE DRUG CI-LAO-YIA--THE BARK OF ARALIA MANDSHURICA RUPR. ET MAXIM.] FU KC, HSU SK, WU RH, KAO KB. Yao Xue Xue Bao. 1964 Dec;11:824-33. Chinese. No abstract available. PMID: 14254783
[PHARMACOLOGY OF ARALIA MANDSHURICA.] KIRIUTINA VI. Farmakol Toksikol. 1964 Nov-Dec;27:701-2. Russian. No abstract available. PMID: 14321296
[The antistress effect of the saponinic summ extracted from roots of Aralia mandshurica cultivated in Moldavia] Lupusoru CE, Zagnat M, Ghiciuc CM, Lupusoru R, Stanescu U, Grigorescu E. Rev Med Chir Soc Med Nat Iasi. 2008 Oct-Dec;112(4):1092-7. Romanian. PMID: 20209793

Schizandra chinensis
Isolation of lignans from Schisandra chinensis with anti-proliferative activity in human colorectal carcinoma: Structure-activity relationships. Gnabre J, Unlu I, Chang TC, Lisseck P, Bourne B, Scolnik R, Jacobsen NE, Bates R, Huang RC. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Aug 14. [Epub ahead of print]PMID: 20810329
Protective effects of dibenzocyclooctadiene lignans from Schisandra chinensis against beta-amyloid and homocysteine neurotoxicity in PC12 cells. Song JX, Lin X, Wong RN, Sze SC, Tong Y, Shaw PC, Zhang YB. Phytother Res. 2010 Aug 24. [Epub ahead of print]PMID: 20740476
Anti-inflammatory effects of gomisin N, gomisin J, and schisandrin C isolated from the fruit of Schisandra chinensis. Oh SY, Kim YH, Bae DS, Um BH, Pan CH, Kim CY, Lee HJ, Lee JK. Biosci Biotechnol Biochem. 2010;74(2):285-91. Epub 2010 Feb 7.PMID: 20139628
Structural identification and antioxidant properties of major anthocyanin extracted from Omija (Schizandra chinensis) fruit. Kim SH, Joo MH, Yoo SH.
J Food Sci. 2009 Mar;74(2):C134-40.PMID: 19323727
Anti-inflammatory effects of schisandrin isolated from the fruit of Schisandra chinensis Baill. Guo LY, Hung TM, Bae KH, Shin EM, Zhou HY, Hong YN, Kang SS, Kim HP, Kim YS. Eur J Pharmacol. 2008 Sep 4;591(1-3):293-9. Epub 2008 Jun 27.PMID: 18625216
Pharmacology of Schisandra chinensis Bail.: an overview of Russian research and uses in medicine. Panossian A, Wikman G. J Ethnopharmacol. 2008 Jul 23;118(2):183-212. Epub 2008 Apr 24. Review.PMID: 18515024
Extracts from Schizandra chinensis fruit activate estrogen receptors: a possible clue to its effects on nitric oxide-mediated vasorelaxation. Lee YJ, Cho JY, Kim JH, Park WK, Kim DK, Rhyu MR. Biol Pharm Bull. 2004 Jul;27(7):1066-9.PMID: 15256741
[Phytotherapeutic aspects of diseases of the circulatory system. 8. Chinese magnolia (Schisandra chinensis (Turcz.) Baill.): production of the drugs and their evaluation, therapeutic and dietary preparations] Opletal L, Krenková M, Havlícková P. Ceska Slov Farm. 2001 Sep;50(5):219-24. Czech. PMID: 11579687
Improvement of phase I drug metabolism with Schisandra chinensis against CCl4 hepatotoxicity in a rat model. Zhu M, Yeung RY, Lin KF, Li RC. Planta Med. 2000 Aug;66(6):521-5.PMID: 10985077
Evaluation of the protective effects of Schisandra chinensis on Phase I drug metabolism using a CCl4 intoxication model. Zhu M, Lin KF, Yeung RY, Li RC. J Ethnopharmacol.
[Biochemical and pharmacologic effects of wuweizi (Schizandra chinensis (Turcz.) Baill.) and its chemical contents on animal livers] Liu GT. Sheng Li Ke Xue Jin Zhan. 1988 Jul;19(3):197-203. Review. Chinese. No abstract available. PMID: 3074486
Antihepatotoxic actions of lignoids from Schizandra chinensis fruits. Hikino H, Kiso Y, Taguchi H, Ikeya Y. Planta Med. 1984 Jun;50(3):213-8. No abstract available. PMID: 6091164
[On the effectiveness of the juice of schizandra chinensis in thrombocytopenia] Lapaev II. Voen Med Zh. 1965 Jan;1:79-80. Russian. No abstract available. PMID: 5834450
[On the utilization of an experimental form of hypertension in the evaluation of the effectiveness of Schizandra chinensis in atherosclerosis.] VOLYNSKII ZM, MUKUSHKIN MK. Biull Eksp Biol Med. 1960 Nov;50:66-70. Russian. No abstract available. PMID: 13782050
[Results of laboratory-clinical investigations of stimulating and tonic effect of Schizandra chinensis and of ginseng in normal and pathological conditions in animal and man.] SOROKHTIN GN. Farmakol Toksikol. 1955 May-Jun;18(3):53-5. Russian. No abstract available. PMID: 13241565
[Stimulation of labor with Schizandra chinensis.] TRIFONOVA AT. Akush Ginekol (Mosk). 1954 Jul-Aug;4:19-22. Russian. No abstract available. PMID: 13217935

Euterpe oleracea
Effects of an Extract Obtained from Fruits of Euterpe Oleracea Mart. in the Components of Metabolic Syndrome Induced in C57BL/6J Mice Fed a High-Fat Diet. de Oliveira PR, da Costa CA, de Bem GF, Marins de Cavalho LC, de Sousa MA, de Lemos Neto M, da Cunha Sousa PJ, de Moura RS, Resende AC. J Cardiovasc Pharmacol. 2010 Aug 31. [Epub ahead of print]PMID: 20838232
Berries from South America: a comprehensive review on chemistry, health potential, and commercialization. Schreckinger ME, Lotton J, Lila MA, de Mejia EG. J Med Food. 2010 Apr;13(2):233-46.PMID: 20170356
Açai palm fruit (Euterpe oleracea Mart.) pulp improves survival of flies on a high fat diet. Sun X, Seeberger J, Alberico T, Wang C, Wheeler CT, Schauss AG, Zou S. Exp Gerontol. 2010 Mar;45(3):243-51. Epub 2010 Jan 18.PMID: 20080168
Diet supplementation with acai (Euterpe oleracea Mart.) pulp improves biomarkers of oxidative stress and the serum lipid profile in rats. de Souza MO, Silva M, Silva ME, Oliveira Rde P, Pedrosa ML. Nutrition. 2010 Jul-Aug;26(7-8):804-10. Epub 2009 Dec 22.PMID: 20022468
[Correlation between antioxidant activity and bioactive compounds of açaí (Euterpe oleracea Mart) comercial pulps] Santos GM, Maia GA, Sousa PH, Costa JM, Figueiredo RW, Prado GM. Arch Latinoam Nutr. 2008 Jun;58(2):187-92. Portuguese. PMID: 18833997
Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich acai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers.  Mertens-Talcott SU, Rios J, Jilma-Stohlawetz P, Pacheco-Palencia LA, Meibohm B, Talcott ST, Derendorf H. J Agric Food Chem. 2008 Sep 10;56(17):7796-802. Epub 2008 Aug 12.PMID: 18693743
Lignans and other constituents of the fruits of Euterpe oleracea (Acai) with antioxidant and cytoprotective activities. Chin YW, Chai HB, Keller WJ, Kinghorn AD. J Agric Food Chem. 2008 Sep 10;56(17):7759-64. Epub 2008 Jul 26.PMID: 18656934
Chemical composition, antioxidant properties, and thermal stability of a phytochemical enriched oil from Acai (Euterpe oleracea Mart.). Pacheco-Palencia LA, Mertens-Talcott S, Talcott ST. J Agric Food Chem. 2008 Jun 25;56(12):4631-6. Epub 2008 Jun 4.PMID: 18522407
Absorption and biological activity of phytochemical-rich extracts from açai (Euterpe oleracea Mart.) pulp and oil in vitro. Pacheco-Palencia LA, Talcott ST, Safe S, Mertens-Talcott S. J Agric Food Chem. 2008 May 28;56(10):3593-600. Epub 2008 Apr 29.PMID: 18442253
[Characterization of the acai or manaca (Euterpe oleracea Mart.): a fruit of the Amazon] Neida S, Elba S. Arch Latinoam Nutr. 2007 Mar;57(1):94-8. Spanish. PMID: 17824205
Total oxidant scavenging capacity of Euterpe oleracea Mart. (açaí) seeds and identification of their polyphenolic compounds. Rodrigues RB, Lichtenthäler R, Zimmermann BF, Papagiannopoulos M, Fabricius H, Marx F, Maia JG, Almeida O. J Agric Food Chem. 2006 Jun 14;54(12):4162-7.PMID: 16756342
Açai (Euterpe oleracea Mart.) polyphenolics in their glycoside and aglycone forms induce apoptosis of HL-60 leukemia cells. Del Pozo-Insfran D, Percival SS, Talcott ST. J Agric Food Chem. 2006 Feb 22;54(4):1222-9.PMID: 16478240
Total oxidant scavenging capacities of Euterpe oleracea Mart. (Açaí) fruits. Lichtenthäler R, Rodrigues RB, Maia JG, Papagiannopoulos M, Fabricius H, Marx F. Int J Food Sci Nutr. 2005 Feb;56(1):53-64.PMID: 16019315

Punica Granatum
Protective effects of Punica granatum in experimentally-induced gastric ulcers. Alam MS, Alam MA, Ahmad S, Najmi AK, Asif M, Jahangir T. Toxicol Mech Methods. 2010 Sep 16. [Epub ahead of print]PMID: 20846023
Broad spectrum antimutagenic activity of antioxidant active fraction of Punica granatum L. peel extracts. Zahin M, Aqil F, Ahmad I. Mutat Res. 2010 Aug 11. [Epub ahead of print]PMID: 20708098
Efficacy of Punica granatum extract on in-vitro and in-vivo control of Trichomonas vaginalis. El-Sherbini GM, Ibrahim KM, El Sherbiny ET, Abdel-Hady NM, Morsy TA. J Egypt Soc Parasitol. 2010 Apr;40(1):229-44.PMID: 20503601
The influence of pomegranate by-product and punicalagins on selected groups of human intestinal microbiota. Bialonska D, Ramnani P, Kasimsetty SG, Muntha KR, Gibson GR, Ferreira D. Int J Food Microbiol. 2010 Jun 15;140(2-3):175-82. Epub 2010 Apr 2.PMID: 20452076
Cancer chemoprevention by pomegranate: laboratory and clinical evidence. Adhami VM, Khan N, Mukhtar H. Nutr Cancer. 2009 Nov;61(6):811-5. Review.PMID: 20155621
Pomegranate and breast cancer: possible mechanisms of prevention. Sturgeon SR, Ronnenberg AG. Nutr Rev. 2010 Feb;68(2):122-8. Review.PMID: 20137057
Colon cancer chemopreventive activities of pomegranate ellagitannins and urolithins. Kasimsetty SG, Bialonska D, Reddy MK, Ma G, Khan SI, Ferreira D. J Agric Food Chem. 2010 Feb 24;58(4):2180-7.PMID: 20112993
Pomegranate ellagitannin-derived compounds exhibit antiproliferative and antiaromatase activity in breast cancer cells in vitro. Adams LS, Zhang Y, Seeram NP, Heber D, Chen S. Cancer Prev Res (Phila). 2010 Jan;3(1):108-13.PMID: 20051378
Pomegranate extract induces apoptosis in human prostate cancer cells by modulation of the IGF-IGFBP axis. Koyama S, Cobb LJ, Mehta HH, Seeram NP, Heber D, Pantuck AJ, Cohen P. Growth Horm IGF Res. 2010 Feb;20(1):55-62. Epub 2009 Oct 22.PMID: 19853487
Effects of consumption of pomegranate juice on carotid intima-media thickness in men and women at moderate risk for coronary heart disease. Davidson MH, Maki KC, Dicklin MR, Feinstein SB, Witchger M, Bell M, McGuire DK, Provost JC, Liker H, Aviram M. Am J Cardiol. 2009 Oct 1;104(7):936-42.PMID: 19766760
Pomegranate juice polyphenols increase recombinant paraoxonase-1 binding to high-density lipoprotein: studies in vitro and in diabetic patients. Fuhrman B, Volkova N, Aviram M. Nutrition. 2010 Apr;26(4):359-66. Epub 2009 Sep 17.PMID: 19762215
In vitro and In vivo Antibacterial Activity of Punica granatum Peel Ethanol Extract Against Salmonella. Choi JG, Kang OH, Lee YS, Chae HS, Oh YC, Brice OO, Kim MS, Sohn DH, Kim HS, Park H, Shin DW, Rho JR, Kwon DY. Evid Based Complement Alternat Med. 2009 Aug 17. [Epub ahead of print]PMID: 19687188
Antimicrobial activity of pomegranate (Punica granatum L.) fruit peels. Al-Zoreky NS. Int J Food Microbiol. 2009 Sep 15;134(3):244-8. Epub 2009 Jul 12.PMID: 19632734
The role of pomegranate (Punica granatum L.) in colon cancer. Khan SA. Pak J Pharm Sci. 2009 Jul;22(3):346-8.PMID: 1955318
Pomegranate: its role in cardiovascular health. Ross SM. Holist Nurs Pract. 2009 May-Jun;23(3):195-7. No abstract available. PMID: 19411998
Embryo protective effect of pomegranate (Punica granatum L.) fruit extract in adriamycin-induced oxidative stress. Kishore RK, Sudhakar D, Parthasarathy PR. Indian J Biochem Biophys. 2009 Feb;46(1):106-11.PMID: 19374262
Pomegranate juice: a heart-healthy fruit juice. Basu A, Penugonda K. Nutr Rev. 2009 Jan;67(1):49-56. Review.PMID: 19146506
Pomegranate juice is potentially better than apple juice in improving antioxidant function in elderly subjects. Guo C, Wei J, Yang J, Xu J, Pang W, Jiang Y. Nutr Res. 2008 Feb;28(2):72-7.PMID: 19083391
Antidiabetic effect of Punica granatum flowers: effect on hyperlipidemia, pancreatic cells lipid peroxidation and antioxidant enzymes in experimental diabetes. Bagri P, Ali M, Aeri V, Bhowmik M, Sultana S. Food Chem Toxicol. 2009 Jan;47(1):50-4. Epub 2008 Oct 4.PMID: 18950673
Therapeutic applications of pomegranate (Punica granatum L.): a review. Jurenka JS. Altern Med Rev. 2008 Jun;13(2):128-44. Review.PMID: 18590349

Opuntia ficus-indica
Potent virucidal effect of pheophorbide a and pyropheophorbide a on enveloped viruses. Bouslama L, Hayashi K, Lee JB, Ghorbel A, Hayashi T. J Nat Med. 2010 Sep 11. [Epub ahead of print]PMID: 20835849
Determination of Antioxidant Constituents in Cactus Pear Fruits. Fernández-López JA, Almela L, Obón JM, Castellar R. Plant Foods Hum Nutr. 2010 Sep 2. [Epub ahead of print]PMID: 20811778
Comparative evaluation of two different Opuntia ficus-indica extracts for blood sugar lowering effects in rats. Butterweck V, Semlin L, Feistel B, Pischel I, Bauer K, Verspohl EJ. Phytother Res. 2010 Aug 4. [Epub ahead of print]PMID: 20687136
By-Products of Opuntia ficus-indica as a Source of Antioxidant Dietary Fiber. Bensadón S, Hervert-Hernández D, Sáyago-Ayerdi SG, Goñi I. Plant Foods Hum Nutr. 2010 Jul 10. [Epub ahead of print]PMID: 20623195
Medicinal agents in the metabolic syndrome. Baños G, Pérez-Torres I, El Hafidi M. Cardiovasc Hematol Agents Med Chem. 2008 Oct;6(4):237-52. Review.PMID: 18855636
Opuntia ficus indica's effect on heart-rate variability in high-level athletes. Schmitt L, Fouillot JP, Nicolet G, Midol A. Int J Sport Nutr Exerc Metab. 2008 Apr;18(2):169-78.PMID: 18458360
Betanin a betacyanin pigment purified from fruits of Opuntia ficus-indica induces apoptosis in human chronic myeloid leukemia Cell line-K562. Sreekanth D, Arunasree MK, Roy KR, Chandramohan Reddy T, Reddy GV, Reddanna P. Phytomedicine. 2007 Nov;14(11):739-46. Epub 2007 May 7.PMID: 17482444
Opuntia ficus-indica attenuates neuronal injury in in vitro and in vivo models of cerebral ischemia. Kim JH, Park SM, Ha HJ, Moon CJ, Shin TK, Kim JM, Lee NH, Kim HC, Jang KJ, Wie MB. J Ethnopharmacol. 2006 Mar 8;104(1-2):257-62. Epub 2005 Oct 21.PMID: 16243466
Supplementation with cactus pear (Opuntia ficus-indica) fruit decreases oxidative stress in healthy humans: a comparative study with vitamin C. Tesoriere L, Butera D, Pintaudi AM, Allegra M, Livrea MA. Am J Clin Nutr. 2004 Aug;80(2):391-5.PMID: 15277160
Modulation of intracellular calcium concentrations and T cell activation by prickly pear polyphenols. Aires V, Adote S, Hichami A, Moutairou K, Boustani ES, Khan NA. Mol Cell Biochem. 2004 May;260(1-2):103-10.PMID: 15228091
Effect of Opuntia ficus indica on symptoms of the alcohol hangover. Wiese J, McPherson S, Odden MC, Shlipak MG. Arch Intern Med. 2004 Jun 28;164(12):1334-40.PMID: 15226168
Neuroprotective effects of antioxidative flavonoids, quercetin, (+)-dihydroquercetin and quercetin 3-methyl ether, isolated from Opuntia ficus-indica var. saboten. Dok-Go H, Lee KH, Kim HJ, Lee EH, Lee J, Song YS, Lee YH, Jin C, Lee YS, Cho J. Brain Res. 2003 Mar 7;965(1-2):130-6.PMID: 12591129
Antiulcer activity of Opuntia ficus indica (L.) Mill. (Cactaceae): ultrastructural study. Galati EM, Monforte MT, Tripodo MM, d'Aquino A, Mondello MR. J Ethnopharmacol. 2001 Jun;76(1):1-9.PMID: 11378276
An anti-inflammatory principle from cactus. Park EH, Kahng JH, Lee SH, Shin KH. Fitoterapia. 2001 Mar;72(3):288-90.PMID: 11295308
Wound healing activity of Opuntia ficus-indica. Park EH, Chun MJ. Fitoterapia. 2001 Feb;72(2):165-7.PMID: 11223226
Studies on the pharmacological action of cactus: identification of its anti-inflammatory effect. Park EH, Kahng JH, Paek EA. Arch Pharm Res. 1998 Feb;21(1):30-4.PMID: 9875511
[Effect of a dehydrated extract of nopal (Opuntia ficus indica Mill.) on blood glucose] Frati-Munari AC, de León C, Ariza-Andraca R, Bañales-Ham MB, López-Ledesma R, Lozoya X. Arch Invest Med (Mex). 1989 Jul-Sep;20(3):211-6. Spanish. PMID: 2561256

Ananas comosus

In vivo antitumoral activity of stem pineapple (Ananas comosus) bromelain. Báez R, Lopes MT, Salas CE, Hernández M. Planta Med. 2007 Oct;73(13):1377-83. Epub 2007 Sep 24.PMID: 17893836
Effect of ethanolic extracts of Ananas comosus L. leaves on insulin sensitivity in rats and HepG2. Xie W, Wang W, Su H, Xing D, Pan Y, Du L. Comp Biochem Physiol C Toxicol Pharmacol. 2006 Aug;143(4):429-35. Epub 2006 Apr 28.PMID: 16753349
Diuretic effects of selected Thai indigenous medicinal plants in rats. Sripanidkulchai B, Wongpanich V, Laupattarakasem P, Suwansaksri J, Jirakulsomchok D. J Ethnopharmacol. 2001 May;75(2-3):185-90.PMID: 11297849
Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update. Taussig SJ, Batkin S. J Ethnopharmacol. 1988 Feb-Mar;22(2):191-203. Review.PMID: 3287010
Modulation of pulmonary metastasis (Lewis lung carcinoma) by bromelain, an extract of the pineapple stem (Ananas comosus) Batkin S, Taussig S, Szekerczes J. Cancer Invest. 1988;6(2):241-2. No abstract available. PMID: 3378194
Inhibition of Tumour Growth in vitro by Bromelain, an Extract of the Pineapple Plant (Ananas comosus). Taussig SJ, Szekerczes J, Batkin S. Planta Med. 1985 Dec;51(6):538-9. No abstract available. PMID: 17345291
Ascorbic acid and physiological breakdown in the fruits of the pineapple (Ananas comosus L. Merr). MILLER EV, HEILMAN AS. Science. 1952 Nov 7;116(3019):505-6. No abstract available. PMID: 13015097
PHYSIOLOGICAL STUDIES OF THE FRUITS OF THE PINEAPPLE [ANANAS COMOSUS (L.) MERR.] WITH SPECIAL REFERENCE TO PHYSIOLOGICAL BREAKDOWN. Miller EV. Plant Physiol. 1951 Jan;26(1):66-75. No abstract available. PMID: 16654359

Pyrus malus y Pyrus communis
Daily consumption of apple, pear and orange juice differently affects plasma lipids and antioxidant capacity of smoking and non-smoking adults. Alvarez-Parrilla E, De La Rosa LA, Legarreta P, Saenz L, Rodrigo-García J, González-Aguilar GA. Int J Food Sci Nutr. 2010 Jun;61(4):369-80.PMID: 20109132
A low-energy-dense diet adding fruit reduces weight and energy intake in women. de Oliveira MC, Sichieri R, Venturim Mozzer R. Appetite. 2008 Sep;51(2):291-5. Epub 2008 Mar 7.PMID: 18439712
Apple and pear peel and pulp and their influence on plasma lipids and antioxidant potentials in rats fed cholesterol-containing diets. Leontowicz M, Gorinstein S, Leontowicz H, Krzeminski R, Lojek A, Katrich E, Cíz M, Martin-Belloso O, Soliva-Fortuny R, Haruenkit R, Trakhtenberg S. J Agric Food Chem. 2003 Sep 10;51(19):5780-5.PMID: 12952433
Weight loss associated with a daily intake of three apples or three pears among overweight women. Conceição de Oliveira M, Sichieri R, Sanchez Moura A. Nutrition. 2003 Mar;19(3):253-6.PMID: 12620529
Antioxidant and antiproliferative activities of common fruits. Sun J, Chu YF, Wu X, Liu RH. J Agric Food Chem. 2002 Dec 4;50(25):7449-54.PMID: 12452674
Algunos estudios recientes sobre DHA
Alta presión arterial. Un estudio sobre hipertensión mostró que DHA pero no EPA disminuyó la presión sanguínea. Hypertension. 1999;34(2):253-60.
Cuando los triglicéridos son elevados. Un estudio en el American Journal of Clinical Nutrition mostró que DHA puede disminuir los triglicéridos. Am J Clin Nutr. 2004;79:765-73.
El masivo Estudio de Corazón Framingham mostró que tomar DHA puede mejorar la función mental, reducir el declinamiento cognitivo y evitó el Alzheimer.
Un estudio publicado en "Archivos de Neurología" demostró que mayores niveles de DHA están asociados con un menor riesgo de demencia. Arch Neurol. 2006;63:1545-50.
Uno de los signos de un atleta de resistencia bien entrenado es un reducido latido de corazón en reposo. DHA (y no EPA ni un placebo) mostró reducir el latido del corazón por más de 3 latidos por minuto en un estudio de The Journal Hypertension. Hypertension. 1999;34(2):253-60.
DHA es necesario para la función de contracción rápida de la fibra muscular. Cualquier deportista del tipo de fuerza explosiva (o personal de operaciones especiales) deberían aumentar su ingesta de DHA. Am J of Physiological Endocrinology and Metabolism 279 (2000): E744-51
Para cualquier persona con problemas de vista, esta investigación ha mostrado que una dieta rica en DHA ayuda a prevenir la degeneración macular. Br J Ophthalmol. 2009;93(9):1241-6
Niveles elevados de DHA están correlacionados con mayores metabolismos. Esta investigación es realmente sorprendente. Los investigadores encontraron que los animales con masa idéntica pudieran tener drásticamente diferentes tasas metabólicas, y mayores tasas metabólicas siempre fueron asociadas con mayores niveles de DHA. Journal of Theoretical Biology 199 (1999): 257-74; American Journal of Physiology 240 (1981): R3-9.
Los niños que tomaron suplemento de DHA pueden tener mayores índices de coeficiente intelectual. A pesar de que la inteligencia es dificil de medir y controlar, muchos estudios han mostrado una conexión. Hay que tener en cuenta que los investigadores, por naturaleza, no realizan conclusiones dogmáticas, pero los resultados en muchos estudios son muy impresionantes, sin inconvenientes para suplementar con DHA. Am J Clin Nutr 2009 Feb;89(2):678S-84S
DHA apoya el desarrollo neural del feto. De nuevo, mientras no es absolutamente concluyente, el grueso de la investigación sugiere una fuerte correlación entre los niveles de DHA y el desarrollo neural. Early Hum Dev. 2010 Feb 2; Am J Clin Nutr 2009 Feb;89(2):678S-84S.
Niveles de DHA asociados con los riesgos de Diabetes tipo II. Como se vió en los esquimales de Groenlandia en los 70s (altos niveles de DHA y baja ocurrencia de diabetes) y los indios Pima (bajo nivel de DHA y alta ocurrencia de diabetes). Allport, Susan, The Queen of Fats. Los Angeles: University of California Press, 2006; Lancet, June 5, 1971, p. 1144
DHA podría retardar o detener la progresión del cáncer de seno. Un estudio en el International Journal of Oncology concluyó que DHA podría retardar la "proliferación de células tumorales, y minimizar su potencial de metástasis" Int J Oncol. 2010 Mar;36(3):737-42.
DHA podría inhibir el crecimiento de tumor y proliferación en el cáncer colorrectal. Muchos estudios muestran una fuerte conexión en la capacidad de DHA para alterar la progresión del cáncer de colon. J Lipid Res 2008 Oct;49(10):2089-100; World J Gastroenterol. 2009 Mar 7;15(9):1079-84; Lipids 2009 Aug;44(8):673-83.
En Febrero de 2010, el American Journal of Clinical Nutrition publicó que un 70% de incremento en concentración de DHA en  membranas fue visto en tan poco como 1,200 mg. por día después de 8 semanas. Am J Clin Nutr. 2010 Feb. 3.

Otras investigaciones relacionadas
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Ion channels in toxicology.Restrepo-Angulo I, De Vizcaya-Ruiz A, Camacho J. J Appl Toxicol. 2010 Aug;30(6):497-512.PMID: 20583319
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The metabolic component of cellular refractivity and its importance for optical cytometry. Tychinsky V. J Biophotonics. 2009 Sep;2(8-9):494-504.PMID: 19644930
Structured water in partially dehydrated yeast cells and at partially hydrophobized fumed silica surface. Turov VV, Gun'ko VM, Bogatyrev VM, Zarko VI, Gorbik SP, Pakhlov EM, Leboda R, Shulga OV, Chuiko AA. J Colloid Interface Sci. 2005 Mar 15;283(2):329-43.PMID: 15721902
Importance of interfacial water in permeabilization of ceramide bilayers. Neitchev V, Kostova E, Dimitrov AS. Histol Histopathol. 1998 Jul;13(3):911-20. Review.PMID: 9690145
Successful therapy of heart disease by high potassium together with low sodium in accord with predictions from the associated cation, structured water concept of the cell. Cope FW. Physiol Chem Phys. 1979;11(1):93-4.PMID: 504367
Pathology of structured water and associated cations in cells (ther tissue damage syndrome) and its medical treatment. Cope FW. Physiol Chem Phys. 1977;9(6):547-53.PMID: 614594
Fluorescent probe environment and the structural and charge changes in energy coupling of mitochondrial membranes. Chance B. Proc Natl Acad Sci U S A. 1970 Oct;67(2):560-71.PMID: 5289010
The influence of pH and temperature on the limited rotational freedom of the structured water and lipid hydrocarbon chains of natural membranes. Cerbón J. Biochim Biophys Acta. 1970 Sep 15;211(3):389-95. No abstract available. PMID: 5456970
National Institute of Health, USA
En estudios conducidos en institutos de investigación, como el National Institutes of Health (NIH), el Southern Research Institute, Bethesda, MD. y la escuela de medicina de la University of Southern California, la capacidad de los ácidos húmicos para interferir con la replicación de virus y el apoyo al sistema inmunológico del cuerpo para erradicar los virus se ha observado en:
- Influenza y el resfriado común
- Hepatitis C
- Virus del Oeste del Nilo
- Herpes oral
- Herpes simplex
Específicamente la investigación del NIH mostró que el ácido húmico es muy efectivo al arrestar la replicación del virus de la influenza, sin importar la variante viral específica.
Virus de Fiebre hemorrágica. "As shown, the (Humic Acids) exhibited substantial efficacy against both hemorrhagic fever viruses….natural-product HA (Humic Acid) particularly so against Punta Toro A virus." National Institutes of Allergy and Infectious Diseases (NIAID), under the auspices of the National Institutes of Health, August 2001 - January 2002
Virus de Herpes Simplex Tipos I y II. "It is therefore concluded that it is possible to test the anti-viral effects of all four (Humic Acid) compounds up to 500 ug/mL without any drug-related cytotoxicity." "Furthermore, three series of experiments were designed to explore the potential mechanisms of action. The first series of experiments demonstrated that all four compounds (of Humic Acid) can inactivate both HSV-1 and HSV-2 infections with different anti-viral activities. The second series of experiments demonstrated that the compounds (of Humic Acid) can protect cells against HSV-1 and HSV-2 infection. The third series of experiments demonstrated that the compounds (of Humic Acid) can interfere with the proliferation of HSV-1 and HSV-2 after the virus enters the cells." Meeta Patnaik, M.D., Senior Research Scientist; Hun-Chi Lin, PhD, Director, Clinical Trials Specialty Laboratories, Santa Monica, CA, August 1998
HIV-1. "…the ability to inhibit the replication of wild-type strains (of HIV-1) is an obvious (and, arguably, the most important) prerequisite in order that any HIV-1 drug be considered useful. The results obtained to date have shown that (natural) Humic Acid as well as synthetic humic acid(s) do, in fact, inhibit the replication of HIV-1 wild-type strains, in addition to assaulting in a unique way the intracellular replicative events of the virus." "It was found in this work that both synthetic as well as naturally-occurring humic substances extracted from soil are in fact capable of inhibiting HIV-1 replication." Research team at USC School of Medicine, January, 1998.
"The Humates are potent inhibitors of acute HIV infection in antiviral evaluation models. The present studies point to an antiviral target occurring before proviral integration, possibly involving virus attachment and entry." "We were able to confirm antiviral activity for the Humates and define their potential antiviral target to the pre-integration phase of HIV replication, providing preliminary data that a portion of the antiviral activity is due to inhibition of virus attachment." Jim A. Turpin Ph.D., Manager Retrovirus Research Laboratory; Tracy Loftus, Supervisor Retrovirus Research Laboratory Southern Research Institute, September, 2000
"(Humic Acid) inhibited HIV-1 infection of MT-2 cells with an IC(50) of 12.5 microg/ml. Treatment of free and cell-attached HIV with (Humic Acid) irreversibly reduced infectivity, while the susceptibility of target cells to the virus was not impaired by treatment prior to infection. The infectivity of the HIV particles was inhibited by interference with CD4 binding and the V3 loop-mediated step of virus entry. No viral resistance to (Humic Acid) developed over a 12-week period in vitro. (Humic Acid) therefore holds promise for the treatment of HIV-infected patients." van Rensburg CE, Department of Pharmacology, University of Pretoria, Pretoria, South Africa; Dekker J, Enerkom (Pty) Ltd, Pretoria, South Africa; Weis R, Smith TL, Janse van Rensburg E, Schneider J.
"Humic acids are natural constituents of soil and ground water and mainly consist of mixtures of polycyclic phenolic compounds. (Humic Acid) inhibited HIV-1 infection of MT-2 cells with an IC50 of 50-300 ng/ml. Inhibition of HIV-induced syncytium formation was observed at 10-50 micrograms/ml. Treatment of free and cell-attached HIV with (Humic Acid) irreversibly reduced its infectivity. (Humic Acid) interfered with the CD4-induced proteolytic cleavage of the V3 loop of virion gp120SU. Furthermore, binding of V3 loop-specific antibodies was irreversibly inhibited, whereas binding of soluble CD4 to gp120SU on virus and infected cells was not affected. In conclusion, our data suggest, that the (Humic Acid) inhibits the infectivity of HIV particles by interference with a V3 loop-mediated step of virus entry." Schneider J, Weis R, Manner C, Kary B, Werner A, Seubert BJ, Riede UN. Abteilung Virologie, Institut fur Medizinische Mikrobiologie und Hygiene der Universitat, Freiburg, Germany.
"The anti-HIV-1 activity of the new humic acid derivative has been determined in vitro, and the serial passages at low concentrations have been performed to investigate the emergence of resistance to this drug candidate." "Our investigations were performed to find perspective compounds and their combinations to employ them in topical microbicides which possess the ability to block the HIV transmission on different stages of virus cell interaction. We have studied original compounds from different groups: sulfated chitosanes, humic acids and plant polyphenol derivatives." "The ED50 values of the humic acid derivatives against HIV-1 laboratory strain and HIV-1 M-tropic AZT-resistant wild-type strain were 0.85 and 3.5 mg/ml respectively, without appearance of any detectible resistance." "The new humic acid derivative is an effective inhibitor of various HIV strains. According to our data, this compound disorders HIV replication and yields defective un-infectious virions." Edward Karamov PhD, Director of Immunochemistry Group, Ivanovsky Inst. of Virology, Moscow, Russia
Viruses de Influenza. "…natural-product humate(s) (Humic Acid) were found to be quite effective against all three influenza viruses." National Institutes of Allergy and Infectious Diseases (NIAID), under the auspices of the National Institutes of Health, August 2001 - January 2002
Humic Acid inhibits the in-vitro replication of influenza virus A/WSN/33 (H1N1) in Madin-Darby canine kidney (MDCK) cells at concentrations of no cytotoxicity. The IC50 for Humic Acid was 48.61 +/- 7.32 microg/ml and 55.27 +/- 5.46 microg/ml respectively when the compound was added at the stage of viral adsorption or post-adsorption. Humic acid inhibits the endonuclease activity of viral RNA polymerase. Lu FJ, Tseng SN, Li ML, Shih SR. Department of Biochemistry, College of Medicine, National Taiwan University, Taipei.
Pruebas de Toxicidad. "For each sample, three concentrations of test article (Humic Acid) were prepared… and each injected into the tail veins of 10 Swiss Webster mice… at dose levels of 50 mg/kg of body weight, 25 mg/kg, and 12.5 mg/kg… the mice were examined for symptoms of toxicity for 14 days. All animals survived the test, and in my opinion, the clinical observations made were not indicative of toxicity."Richard Schlesinger, Ph.D., D.A.B.F.T. BioScreen Testing Services, Inc., Torrance, CA, August 1998
"All (Humic Acids) evaluated were not cytotoxic at levels at least as high as 100 mg/mL…" National Institutes of Allergy and Infectious Diseases (NIAID), under the auspices of the National Institutes of Health, August 2001 - January 2002

Los siguientes son extractos de: "Medical Aspects and Applications of Humic Substances" Acerca de la actividad antiviral de sustancias húmicas. Prof. Dr. Renate Klocking & Dr. rer. nat. Bjorn Helbig. Institute for Antiviral Chemotherapy, Friedrich Schiller University, Jena, Germany
Múltiples virus inhibidos. "Preliminary in-vitro studies with Coxsackie A9 virus, influenza A virus and herpes simplex virus type 1 (HSV-1) have already shown that (Humic Substances) are effective against both naked and enveloped DNA viruses (Klocking and Sprosig, 1972, 1975; Thiel et al., 1977)."
"Further investigations corroborate the ability of (Humic Acid) to inhibit selectively viruses for human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2), cytomegalovirus (CMV) and vaccinia virus (Schols et al., 1991; Neyts et al., 1992)."
Inhibición de Fusión Viral. "With most viruses, the inhibitory effect of (Humic Acid) is directed specifically against an early stage of virus replication, namely virus attachment to cells (Klocking and Sprosig, 1975; Schols et al., 1991; Neyts et al., 1992)."
"…it appears likely that the poly-anionic Humic Acids occupy positively charged domains of the viral envelope glycoproteins, which are necessary for virus attachment to the cell surface (Neyts et al., 1992)."
Herpes. "The effect of (Humic Acids) on an early stage of herpes virus replication has been confirmed by the results of animal experiments. The number of lesions in the cornea of HSV-1-infected rabbits was strongly reduced when a solution of the (Humic Acid) was applied into the conjunctival sac of the eye along with or immediately after the infectious agent."
"Current interest is directed to the prophylactic effect of (Humic Acids) on recurrent HSV infection."
"It is known that topical application of (Humic Acid) may significantly reduce or even completely suppress experimentally induced herpes in the mouse ear (Durre and Schindler, 1992), though the mechanistic basis of this effect remains to be elucidated."
VIH. "A low-molecular weight (Humic Acid) (HS 1500, M.W. = 1500 Daltons), was found to strongly inhibit HIV-1 in vitro (Schneider et al., 1996)."
No irritante. "Studies on the mechanism of action revealed virus penetration into host cells as the target of the anti-HIV-1activity. (Humic Acid) has passed a panel of pre-clinical tests including eye irritation according to Draize, as well as pregnancy risk in rats. Neither sensitizing nor irritating effects were detectable in concentrations of up to 10% HA (Wiegleb et al., 1993; Lange et al., 1996a,b).'
Conclusión. "Taken together, results so far show that HS are promising candidates for prophylactic rather than therapeutic use in the treatment of viral diseases."
NOTA: Esta conclusión está basada solamente en los estudios limitados referidos anteriormente. Estos estudios muestran que el Acido Humico actua primero como prevención porque interfiere con la capacidad del virus para adherirse y penetrar a una célula anfitriona para reproducirse posteriormente. Estudios científicos han demostrado que si una célula anfitriona es penetrada antes de la introducción del Acido Humico, el proceso de reproducción no se detiene pero, como siempre, después de que el virus se reproduce, la célula anfitriona libera los nuevos virus en el flujo sanguíneo; en este punto, si el Acido Humico está presente, puede prevenir que nuevas generaciones de virus invadan células anfitrionas adicionales. Esta es una acción terapéutica que la investigación anterior no verifica específicamente, por eso se concluye esta acción.

Bibliografía seleccionada de Reportes acerca de la eficacia antiviral del Ácido Húmico, recolectados en los últimos 25 años o más:
Investigations on the Viricidal Effects of Humic Acids in Peat-Mull; H. Schultz; Dtsch Tierarztl Wochenschr Jul. 1, 1965. 72(13), pp. 294-297.
Biochemical Study of Humus Action of a Proteolytic Enzyme on Natural and Synthetic Humic Polymers and Those of Microbial Origin. M. Robert Gero, et al; Ann Inst Pasteur (Paris) Dec. 1967, 113(6), pp. 903-909.
Antiviral Properties of Humic Acids; R. Klocking, et al; Experientia May 15, 1972, 28(5), pp. 607-608.
In Vitro Studies of the Antiviral Activity of Ammonium Humate Against Herpes Simplex Virus Type 1 and Type 2; K.D. Thiel, et al; Zentralbl Bakteriol (Orig. A) Nov. 1977, 239(3), pp. 304-321.
Studies on the Antimicrobial Effect on Natural and Synthetic Humic Acids; R. Ansorg; et al; Arzneimittleforschung 1978, 28(12, pp. 2195-2198.
Antiviral Activity of Phenolic Polymers Against Type 1 Herpesvirus Hominis; R. Klocking, et al; Pharmazie Aug. 1978, 33(8), p. 539.
Results of an Oriented Clinical Trial of Ammonium Humate for the Local Treatment of Herpesvirus Hominus (HVH) Infections; F. Schiller, et al; Dermatol Monatsschr Jul. 1979, 165(7), pp. 505-509.
Comparison of the in Vitro Activities of Ammonium Humate and of Enzymically Oxidized Chlorogenic and Caffeic Acids Against Type 1 and Type 2 Human Herpes Virus;K.D. Thiel; et al; Pharmazie 1981, 36(1), pp. 50-53.
Effectiveness of Phenol Body Polymers Against Influenza Virus,R. Mentel, et al; A/KRASNODAR/101/59/H2N2; Biomed Biochim Acta 1983, 42(10), pp. 1353-1356.
Inhibition of Several Strains of Influenza Virus Type A and B by Phenolic Polymers; J. Hills; et al; Biomed Biochim Acta 1986, 45(9), pp. 1173-1179.
The Effect of Phenolic Polymers on Retroviruses; G. Sydow, et al; Pharmazie Dec. 1986, 41(12), pp. 865-868.
Synthesis and Characterization of Humic Acid-Like Polymers; K.I. Hanninen, et al; The Science of the Total Environment 1987, 62, pp. 201-210.
Interaction of Humic Acids and Humic-Acid-Like Polymers with Herpes Simplex Virus Type 1 Humic Substances in the Aquatic and Terrestrial Environment, R. Klocking et al., New York; Springer-Verlag 1989, pp. 407-412.
Synthesis and Anti-Hiv Activities of Low Molecular Weight Aurintricarboxylic Acid Fragments and Related Compounds; M. Cushman, et al; Journal of Medicinal Chemistry 1991, 34(1), pp. 337-342.
Interaction of Humic Acids and Humic-Acid-Like Polymers with Herpes Simplex Virus Type 1; Humic Substances in the Aquatic and Terrestrial Environment, R. Klocking; Berlin 1991, pp. 408-412.
Selective Inhibitory Activity of Polyhydroxycarboxylates Derived From Phenolic Compounds Against Human Immunodeficiency Virus Replication; D. Schols, et al; Journal of Acquired Immune Deficiency Syndromes 1991, 4(7), pp. 677-685.
Treatment of HIV Infection with Humic Acid; WO95/08335 - PCT; Mar. 30, 1995.
Inhibition of HIV-1 in Cell Culture by Synthetic Humate Analogues Derived From Hydroquinone: Mechanism of Inhibition; J. Schneider, et al; Virology 1996, 218(2), pp. 389-395.
Comparison of the Effect of Natural and Synthetic Humates and EDTA on the Growth of Escherichia coli; M. Jakubiec; et al; Abstract not available.
Seffner, W. "Effects of humic acid on the availability of iodine in the food, investigated with the histometric assessment of the thyroid gland". Conference Paper Mengen- und spurenelemente-15 Arbelstagund, 1995.
Bernacci, F. et al. "In vivo and in vitro mutagenicity studies on natural humic acid". Conference paper 37, Riunione scientifica, October 1991.
Gau, R. et al. "Induction of oxidative stress by humic acid through increasing intracellular iron; a possible mechanism leading to atherothrombotic vascular disorder in blackfoot disease". Biochem Biophys Res Commun, 2001; Vol 283; Issue 4: 743-49.
Iubitskaia , NS . "Sodium humate in the treatment of osteoarthritis patients." Vopr Kurortol Fizioter Lech Fiz Kult, 1999; Issue 5, 22-24.
Schiller, F. "Results of an oriented clinical trial of ammonium humate for the local treatment of herpesvirus hominis (HVH) infections". Dermatol Monatsschr, 1979, Vol. 165; Issue 7; 505-09.
Riede, U.N. "Humate induced activation of human granulocytes. Virchows Arch B Cell Pathol Incl Mol Pathol, 1991; Issue 1: 27-34.
Herzig, I. "The effect of sodium humate on cadmium deposition in the organs of chickens". Vet Med, 1994, Vol 39; Issue 4; 175-85.
Hampi, I, et al. "Pharmacokinetics of sodium humate in chickens". Vet Med, 1994; Vol 39, Issue 6; 305-313.
Schneider, J, et al. "Inhibition of HIV-1 in cell culture by synthetic humate analogues derived from hydroquinone; mechanism of inhibition". Virology, 1996; Vol 218, Issue 2, 389-95.
Thiel, KD, et al. "In vitro studies of the antiviral activity of ammonium humate against herpes simplex virus type 1 and type 2". Zentralbl Bakteriol, 1977; Vol. 239, Issue 3, 304-321.
Laub, R. "The chemically induced inhibition of HSV infection". Laub BioChem Corp., August 1998.
Laub, R. "The chemically induced inhibition of HIV-1 replication". Laub BioChem Corp., January 1995.
Nota: Para Alfa PXP Royale aplican los estudios realizados a los polisacáridos péptidos (gliconutrientes) realizados a Alfa PXP Forte. Sin embargo, dadas las características del arroz morado de Alfa PXP Royale, cuyo color morado se debe al alto contenido en antioxidantes como la antocianina, la información se complementa con los siguientes estudios.

Yao Y, Sang W, Zhou M, Ren G. Institute of Crop Science, Chinese Academy of Agricultural Sciences, No 80 South Xueyuan Road, Haidian District, Beijing 100081, People's Republic of China. Antioxidant and alpha-glucosidase inhibitory activity of colored grains in China. J Agric Food Chem. 2010 Jan 27;58(2):770-4. PMID: 19904935
Molecular characterization of OsPAP2: transgenic expression of a purple acid phosphatase up-regulated in phosphate-deprived rice suspension cells. Hur YJ, Jin BR, Nam J, Chung YS, Lee JH, Choi HK, Yun DJ, Yi G, Kim YH, Kim DH. Biotechnol Lett. 2010 Jan;32(1):163-70. Epub 2009 Oct 17.PMID: 19838636
Elemental content in brown rice by inductively coupled plasma atomic emission spectroscopy reveals the evolution of asian cultivated rice. Zeng Y, Wang L, Du J, Liu J, Yang S, Pu X, Xiao F. J Integr Plant Biol. 2009 May;51(5):466-75. Epub 2009 Apr 8.PMID: 19508358
Characteristics of bread prepared from wheat flours blended with various kinds of newly developed rice flours. Nakamura S, Suzuki K, Ohtsubo K. J Food Sci. 2009 Apr;74(3):E121-30.PMID: 19397717
Antioxidant activities of purple rice bran extract and its effect on the quality of low-NaCl, phosphate-free patties made from channel catfish (Ictalurus punctatus) belly flap meat. Min B, Chen MH, Green BW. J Food Sci. 2009 Apr;74(3):C268-77.PMID: 19397712
Delimitation of the PSH1(t) gene for rice purple leaf sheath to a 23.5 kb DNA fragment. Wang WY, Ding HF, Li GX, Jiang MS, Li RF, Liu X, Zhang Y, Yao FY. Genome. 2009 Mar;52(3):268-74.PMID: 19234555
Lipophilic and hydrophilic antioxidants and their antioxidant activities in purple rice bran. Jang S, Xu Z. J Agric Food Chem. 2009 Feb 11;57(3):858-62.PMID: 19138081
The anti-photooxidation of anthocyanins-rich leaves of a purple rice cultivar. Peng C, Lin Z, Lin G, Chen S. Sci China C Life Sci. 2006 Dec;49(6):543-51.PMID: 17312992
Genetic analysis and gene mapping of purple stigma in rice. Han L, Zhang T, Xu JD, Li Y, Wang XD, Wu XJ. Yi Chuan Xue Bao. 2006 Jul;33(7):642-6.PMID: 16875322
Anthocyanin composition in black, blue, pink, purple, and red cereal grains. Abdel-Aal el-SM, Young JC, Rabalski I. J Agric Food Chem. 2006 Jun 28;54(13):4696-704.PMID: 16787017
Antioxidative, antimutagenic, and anticarcinogenic activities of rice bran extracts in chemical and cell assays. Nam SH, Choi SP, Kang MY, Kozukue N, Friedman M. J Agric Food Chem. 2005 Feb 9;53(3):816-22.PMID: 15686439
Cyanidin and Malvidin from Oryza sativa cv. Heugjinjubyeo mediate cytotoxicity against human monocytic leukemia cells by arrest of G(2)/M phase and induction of apoptosis. Hyun JW, Chung HS. J Agric Food Chem. 2004 Apr 21;52(8):2213-7.PMID: 15080622
Antioxidant Activity of Anthocyanin Extract from Purple Black Rice. Ichikawa H, Ichiyanagi T, Xu B, Yoshii Y, Nakajima M, Konishi T. J Med Food. 2001 Winter;4(4):211-218.PMID: 12639403
Comparison of iron bioavailability from 15 rice genotypes: studies using an in vitro digestion/caco-2 cell culture model. Glahn RP, Cheng Z, Welch RM, Gregorio GB. J Agric Food Chem. 2002 Jun 5;50(12):3586-91.PMID: 12033833
The Purple leaf (Pl) locus of rice: the Pl(w) allele has a complex organization and includes two genes encoding basic helix-loop-helix proteins involved in anthocyanin biosynthesis. Sakamoto W, Ohmori T, Kageyama K, Miyazaki C, Saito A, Murata M, Noda K, Maekawa M. Plant Cell Physiol. 2001 Sep;42(9):982-91.PMID: 11577193
Chemical test for mammalian feces in grain products: collaborative study. Gerber HR. J Assoc Off Anal Chem. 1989 Sep-Oct;72(5):766-9.PMID: 2808238
Nota sobre los términos utilizados: ya que los polisacáridos son azúcares, (del griego Glukiz, la primera u se pronuncia como la u francesa) la traducción al latín y por ende a otras lenguas puede variar en la pronunciación, siendo de igual manera aceptadas las raíces gluco- y glico-.

Food and Drugs Administration, USA
Reconocimiento por parte de la FDA (Estados Unidos) al arroz, variedad que está incluida en Alfa PXP Forte:
Rice: FDA Approves Heart, Cancer Health Claim for Brown Rice. http://agfax.com/news/2008/05/brownrice0508.htm
Brown rice wins FDA health claim http://www.alfa-editores.com/web/index.php?option=com_content&task=view&id=1655&Itemid=31
Lea la publicación original de la FDA http://www.fda.gov/OHRMS/DOCKETS/98fr/E8-9590.pdf

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Lefkowitz DL, Stuart R, Gnade BT, Roberts E, Lefkowitz SS. Department of Biological Sciences, Texas Tech University, Lubbock, Texas 79409, USA. Effects of a glyconutrient on macrophage functions. Int J Immunopharmacol. 2000 Apr;22(4):299-308. PMID: 10689103
See DM, Cimoch P, Chou S, Chang J, Tilles J. University of California, Irvine, Department of Medicine, Orange 92668, USA. The in vitro immunomodulatory effects of glyconutrients on peripheral blood mononuclear cells of patients with chronic fatigue syndrome. Integr Physiol Behav Sci. 1998 Jul-Sep;33(3):280-7. PMID: 9829439
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Miquel J. An update on the mitochondrial-DNA mutation hypothesis of cell aging.  Mutation Research 275: 209-16, 1992.
Miquel J. An integrated theory of aging as the result of mitochondrial DNA mutation in differentiated cells. Arch Gerontol Geriatr 12: 99-117, 1991.
Miquel J, Economos AC, Fleming J and Johnson JE. Mitochondrial role in cell aging. Exp Gerontol 15: 575-91, 1980.
Mizuno Y, Ikebe S, Hattori N, Nakagawa-Hattori Y, Mochizuki H, Tanaka M and Ozawa Y. Role of mitochondria in the etiology and pathogenesis of Parkinson’s disease. Biochima et Biophysica Acta
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Otras publicaciones:
Revista de Tecnología del MIT’s Technology Review ~October 2001. “Sugars Could be Biology’s Next Sweet Spot.” En esta edición la revista enfatiza el próximo campo de la biología que está esperando ser explotado: glicanos. Esta disciplina emergente busca mover azúcares y carbohidratos en la mira del desarrollo biomédico y desarrollo de medicamentos.
Science Magazine, Edición Especial. Una publicación de la Universidad de Stanford para la Asociación Americana para el Avance de la Ciencia. Science Magazine dedicó una edición de 200 páginas de la revista para educar a la comunidad científica y médica acerca de los gluconutrientes, glucobiología y glucociencia. 23 de Marzo de 2001.
Physician’s Desk Reference (PDR) for Nonprescription Drugs and Dietary Supplements (Referencia de escritorio de Médicos para Medicamentos sin prescripción y Suplementos Dietéticos) es usada por 99% de médicos y profesionales de la salud antes de recomendar soluciones para sus pacientes, en los Estados Unidos. Los Gluconutrientes / Polisacáridos están enlistados para sistemas inmunológicos comprometidos.
Un estudio,conducido por el Hospital de la Real Armada Tailandesa y el Colegio de Medicina, en conjunto con el Centro de Investigaciones PMK de Bangkok, Tailanda y la Escuela de Medicina de la Universidad Emory, Atlanta, GA, investigaron el efecto protector de los polisacáridos péptidos del arroz en células neuronales expuestas a varias neurotoxinas. Los resultados de estos estudios in-vitro mostraron que cuando las neurotoxinas fueron inducidas, causaban 100% de muerte celular y daño severo a dendritas, las fibras que se extienden del cuerpo de la célula. Cuando las neuronas fueron tratadas previamente con polisacáridos péptidos de arroz, mostraron diferentes niveles de supervivencia celular y recuperación aparente de dendritas de los daños de la neurotoxina dentro de las 48 horas siguientes. Este estudio sugiere que puede haber lugar para los polisacáridos péptidos del arroz en el apoyo y tratamiento de daños cerebrales y enfermedades.
Vic Brozas, Ejecutivo del Corporativo Enzacta desde el 2005 con base en las Filipinas, fue entrevistado para la publicación California Journal for Filipino Americans en su última visita a EE. UU. El artículo destacaba los grandes resultados que Alfa PXP Forte provee por medio del ataque al “Síndrome X”, a la vez que construye una energía física y mental duradera, así como vitalidad y salud. “California Journal for Filipino Americans” es una edición semanal escrita en inglés y distribuida a cientos de empresarios de origen filipino y que están establecidos en los Ángeles y Orange Counties. De acuerdo al censo realizado en el 2000, existe una población de 918,678 filipinos en California. El artículo ayuda al objetivo de Enzacta de crecer dentro de la comunidad filipina. www.cjfilam.com Elegir la edición Oct31-08
IBOBlast 23 de Mayo de 2008, Cita textual: "Desde hace 5 años, el Corporativo Enzacta innovó en la industria de la salud con un suplemento alimenticio a base de arroz.Los beneficios que aporta el Alfa PXP han sido comprobados por miles de personas en México y el mundo, dejando de manifiesto que estamos a la vanguardia en ofrecer a nuestros clientes los mejores avances tecnológicos y de desarrollo en productos para la salud.A pesar de algunas controversias en el tema, hoy finalmente la FDA ha reconocido que el arroz integral es benéfico contra enfermedades del corazón y algunos tipos de cáncer. Este es un evento gigantesco, aseguró Al Montna, director de la Federación de Arroz de Estados Unidos; además comentó: hoy el arroz integral se une a la lista de alimentos reconocidos como saludables. Lo que permitirá que muchos consumidores puedan incrementar el uso del arroz en sus dietas para reducir riesgos de enfermedades del corazón y algunos tipos de cáncer." https://6617001.enzacta.com/Customer/iboblast/media/newiboblast/blast080523.htm
Harpers Biochemistry (Volume 24 Cap. 56). Desde 1996 estos azúcares han sido identificados en Bioquímica, de Harpers, Volumen 24, como glucosa, flucosa, manosa, galactosa, zylosa, anacitelo-glosamina, anacitelogalactosamina y ácido anacitelneromínico. “Comprensive research has led to the discovery of eight monosaccharides needed by every cell in the human body because all eight are required in the engineering and design of life that is coded in our genes.  These sugars are the worlds most powerful, essential carbohydrates and are necessary for proper cellular function and yet research has shown that only two, glucose and galactose are present in the modern diet.” (Traducción: "Investigación compresiva ha llevado al descubrimiento de 8 monosacáridos necesarios por cada célula en el cuerpo humano porque los 8 son requeridos en la ingeniería y diseño de vida que está codificado en nuestros genes. Estos azúcares son los más carbohidratos esenciales más poderosos del mundo y son necesarios para la correcta función celular y aún la investigación ha mostrado que solo dos, glucosa y galactosa, están presentes en la dieta moderna".) Este libro de texto médico (usado en las Universidades Médicas en los Estados Unidos), fue reescrito para incluir un nuevo capítulo sobre glicobiología.
Newsweek (April 25, 1994) presentó una historia que habló del poder de las sustancias en gliconutrientes (polisacáridos) para mejorar ciertos aspectos de las fallas en salud en los Estados Unidos.

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Mattson MP, Furukawa K, Bruce AJ, Mark RJ, Blanc E. Calcium homeostasis and free radical metabolism as convergence points in the pathophysiology of dementia. In: Wasco W. and Tanzi RE., editor. Molecular Mechanisms of Dementia. New Jersey: Humana Press. 1997; 103-43.
Calderon F, et al. PC12 and neuro 2a cells have different susceptibilities to acetylcholinesterase-amyloid complexes, amyloid25-35 fragment, glutamate, and hydrogen peroxide. J Neurosci Res 1999; 56: 620-31.
Munch G, et al. Microglial activation induces cell death, inhibits neurite outgrowth and causes neurite retraction of differentiated neuroblastoma cells. Exp Brain Res 2003; 150: 1-8.
Fabrizi C, Businaro R, Lauro GM, Starace G, Fumagalli L. Activated a2 macroglobulin increase b-amyloid (25-35) induced toxicity in LAN5 human neuroblastoma cells. Experimental Neurol 1999; 155: 252-9.
Behl C, Davis JB, Lesley R, Schubert D. Hydrogen peroxide mediates amyloid beta protein toxicity. Cell 1994; 77: 817-27.
Schubert D, Behl C, Lely R, Brack A, Dargusch R, Sagra Y, et al. Amyloid peptide are toxic via a common oxidative mechanism. Proc Natl Acad Sci USA 1995; 92: 1989-93.
Hansen MB, Nielsen SE, Berg K. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J. Immunol Meth 1989; 119: 203-10.
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Betres-Marquez S.P., Jensen H.H., y Upton J.L. (2005) Trends in rice consumption and contribution of rice to the total diet of Americans. Abstract presented at the Texas Dietetic Association Meeting.
Fulgoni III, V.L., Fulgoni, S.A., Upton, J.L., y Moon, M. (2008) Rice consumption is associated with a greater nutrient density, lower blood pressure, decreased body weight, smaller waist circumference and a reduced risk for metabolic syndrome in adults. Experimental Biology meeting abstracts [on CD- ROM], Abstract #1081. 
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Alfa PXP Forte - Alfa PXP Royale - Alfa HFI - Alfa Energy - Alfa B12 - Alfa DHA - Alfa Yakunaah - Undew Suero facial
Alfa PXP Forte - Alfa PXP Royale - Alfa HFI - Alfa Energy - Alfa B12 - Alfa DHA - Alfa Yakunaah - Undew Suero facial
Alfa PXP Forte - Alfa PXP Royale - Alfa HFI - Alfa Energy - Alfa B12 - Alfa DHA - Alfa Yakunaah - Undew Suero facial
Alfa PXP Forte - Alfa PXP Royale - Alfa HFI - Alfa Energy - Alfa B12 - Alfa DHA - Alfa Yakunaah - Undew Suero facial
Alfa PXP Forte - Alfa PXP Royale - Alfa HFI - Alfa Energy - Alfa B12 - Alfa DHA - Alfa Yakunaah - Undew Suero facial
Alfa PXP Forte - Alfa PXP Royale - Alfa HFI - Alfa Energy - Alfa B12 - Alfa DHA - Alfa Yakunaah - Undew Suero facial
Alfa PXP Forte - Alfa PXP Royale - Alfa HFI - Alfa Energy - Alfa B12 - Alfa DHA - Alfa Yakunaah - Undew Suero facial
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Acacia gen.
Medicinal plants used for the treatment of various skin disorders by a rural community in northern Maputaland, South Africa. De Wet H, Nciki S, van Vuuren SF. J Ethnobiol Ethnomed. 2013 Jul 19;9:51. doi: 10.1186/1746-4269-9-51. PMID: 23870616
Efficacy of Acacia senegal for stoma care in children with colostomy. Hosseinpour M, Fazeli A, Agabeigi M. Eur J Pediatr Surg. 2012 Jun;22(3):234-7. doi: 10.1055/s-0032-1308706. Epub 2012 May 10. PMID: 22576305
Inhibitory Effect of Polyphenol-Rich Fraction from the Bark of Acacia mearnsii on Itching Associated with Allergic Dermatitis. Ikarashi N, Sato W, Toda T, Ishii M, Ochiai W, Sugiyama K. Evid Based Complement Alternat Med. 2012;2012:120389. doi: 10.1155/2012/120389. Epub 2012 Jan 22. PMID: 22315629
Antibacterial activity of extracts of acacia aroma against methicillin-resistant and methicillin-sensitive Staphylococcus. Mattana CM, Satorres SE, Sosa A, Fusco M, Alcará LE. Braz J Microbiol. 2010 Jul;41(3):581-7. doi: 10.1590/S1517-83822010000300007. Epub 2010 Sep 1. PMID: 24031532
Effects of acacia honey on wound healing in various rat models. Iftikhar F, Arshad M, Rasheed F, Amraiz D, Anwar P, Gulfraz M. Phytother Res. 2010 Apr;24(4):583-6. doi: 10.1002/ptr.2990. PMID: 19813239
Antimicrobial activity of pentacyclic triterpenes isolated from Acacia mellifera. Mutai C, Bii C, Rukunga G, Ondicho J, Mwitari P, Abatis D, Vagias C, Roussis V, Kirui J. Afr J Tradit Complement Altern Med. 2008 Oct 25;6(1):42-8. PMID: 20162040
Antimicrobial activity of pentacyclic triterpenes isolated from Acacia mellifera. Mutai C, Bii C, Rukunga G, Ondicho J, Mwitari P, Abatis D, Vagias C, Roussis V, Kirui J. Afr J Tradit Complement Altern Med. 2008 Oct 25;6(1):42-8. PMID: 20162040
Anticancer and antimutagenic properties of Acacia nilotica (Linn.) on 7,12-dimethylbenz(a)anthracene-induced skin papillomagenesis in Swiss albino mice. Meena PD, Kaushik P, Shukla S, Soni AK, Kumar M, Kumar A. Asian Pac J Cancer Prev. 2006 Oct-Dec;7(4):627-32. PMID: 17250441
Antifungal activity of some Tanzanian plants used traditionally for the treatment of fungal infections. Hamza OJ, van den Bout-van den Beukel CJ, Matee MI, Moshi MJ, Mikx FH, Selemani HO, Mbwambo ZH, Van der Ven AJ, Verweij PE. J Ethnopharmacol. 2006 Nov 3;108(1):124-32. Epub 2006 May 22. PMID: 16829001
Final report of the safety assessment of Acacia catechu gum, Acacia concinna fruit extract, Acacia dealbata leaf extract, Acacia dealbata leaf wax, Acacia decurrens extract, Acacia farnesiana extract, Acacia farnesiana flower wax, Acacia farnesiana gum, Acacia senegal extract, Acacia senegal gum, and Acacia senegal gum extract. [No authors listed] Int J Toxicol. 2005;24 Suppl 3:75-118. PMID: 16422266

Te Verde (Camellia Sinensis)
Topical application of green and white tea extracts provides protection from solar-simulated ultraviolet light in human skin. Camouse MM, Domingo DS, Swain FR, Conrad EP, Matsui MS, Maes D, Declercq L, Cooper KD, Stevens SR, Baron ED. Exp Dermatol. 2009 Jun;18(6):522-6. doi: 10.1111/j.1600-0625.2008.00818.x. PMID: 19492999
Green tea polyphenol, (-)-epigallocatechin-3-gallate, induces toxicity in human skin cancer cells by targeting β-catenin signaling. Singh T, Katiyar SK. Toxicol Appl Pharmacol. 2013 Dec 1;273(2):418-24. doi: 10.1016/j.taap.2013.09.021. Epub 2013 Oct 3. PMID: 24096034
Cosmetic benefits of natural ingredients: mushrooms, feverfew, tea, and wheat complex. Bowe WP. J Drugs Dermatol. 2013 Sep;12(9 Suppl):s133-6. PMID: 24002162
The antioxidant property of chitosan green tea polyphenols complex induces transglutaminase activation in wound healing. Qin Y, Guo XW, Li L, Wang HW, Kim W. J Med Food. 2013 Jun;16(6):487-98. doi: 10.1089/jmf.2012.2623. PMID: 23767860
The use of green tea extract in cosmetic formulations: not only an antioxidant active ingredient. Gianeti MD, Mercurio DG, Campos PM. Dermatol Ther. 2013 May-Jun;26(3):267-71. doi: 10.1111/j.1529-8019.2013.01552.x. Epub 2013 Mar 13. PMID: 23742288
Tannase-converted green tea catechins and their anti-wrinkle activity in humans. Hong YH, Jung EY, Shin KS, Yu KW, Chang UJ, Suh HJ. J Cosmet Dermatol. 2013 Jun;12(2):137-43. doi: 0.1111/jocd.12038. PMID: 23725307
[Anti-cancer properties epigallocatechin-gallate contained in green tea]. Donejko M, Niczyporuk M, Galicka E, Przylipiak A. Postepy Hig Med Dosw (Online). 2013 Jan 16;67:26-34. Review. Polish. PMID: 23475480
Green tea in dermatology. Pazyar N, Feily A, Kazerouni A. Skinmed. 2012 Nov-Dec;10(6):352-5. Review. PMID: 23346663
Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. Acnes. Yoon JY, Kwon HH, Min SU, Thiboutot DM, Suh DH. J Invest Dermatol. 2013 Feb;133(2):429-40. doi: 10.1038/jid.2012.292. Epub 2012 Oct 25. PMID: 23096708
Green tea extract: possible mechanism and antibacterial activity on skin pathogens. Sharma A, Gupta S, Sarethy IP, Dang S, Gabrani R. Food Chem. 2012 Nov 15;135(2):672-5. Doi: 10.1016/j.foodchem.2012.04.143. Epub 2012 May 11. PMID: 22868144
Protective mechanisms of green tea polyphenols in skin. OyetakinWhite P, Tribout H, Baron E. Oxid Med Cell Longev. 2012;2012:560682. doi: 10.1155/2012/560682. Epub 2012 Jun 26. Review. PMID: 22792414
Changes in skin mechanical properties after long-term application of cream containing green tea extract. Mahmood T, Akhtar N, Khan BA, Shoaib Khan HM, Saeed T. Aging Clin Exp Res. 2011 Oct-Dec;23(5-6):333-6. PMID: 22526068
Green tea extract protects human skin fibroblasts from reactive oxygen species induced necrosis. Silverberg JI, Jagdeo J, Patel M, Siegel D, Brody N. J Drugs Dermatol. 2011 Oct;10(10):1096-101. PMID: 21968658
Green tea prevents non-melanoma skin cancer by enhancing DNA repair. Katiyar SK. Arch Biochem Biophys. 2011 Apr 15;508(2):152-8. doi: 10.1016/j.abb.2010.11.015. Epub 2010 Nov 19. Review. PMID: 21094124
Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls. Mnich CD, Hoek KS, Virkki LV, Farkas A, Dudli C, Laine E, Urosevic M, Dummer R. Exp Dermatol. 2009 Jan;18(1):69-77. doi: 10.1111/j.1600-0625.2008.00765.x. Epub 2008 Jul 9. PMID: 18631247
Green tea phenol extracts reduce UVB-induced DNA damage in human cells via interleukin-12. Schwarz A, Maeda A, Gan D, Mammone T, Matsui MS, Schwarz T. Photochem Photobiol. 2008 Mar-Apr;84(2):350-5. doi: 10.1111/j.1751-1097.2007.00265.x. Epub 2008 Jan 7. PMID: 18179621
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Te Blanco (Camellia sinensis)
Topical application of green and white tea extracts provides protection from solar-simulated ultraviolet light in human skin. Camouse MM, Domingo DS, Swain FR, Conrad EP, Matsui MS, Maes D, Declercq L, Cooper KD, Stevens SR, Baron ED. Exp Dermatol. 2009 Jun;18(6):522-6. doi: 10.1111/j.1600-0625.2008.00818.x. PMID: 19492999
In vitro studies on release and human skin permeation of Australian tea tree oil (TTO) from topical formulations. Reichling J, Landvatter U, Wagner H, Kostka KH, Schaefer UF. Eur J Pharm Biopharm. 2006 Oct;64(2):222-8. Epub 2006 May 23. PMID: 1684672
Topical application of green and white tea extracts provides protection from solar-simulated ultraviolet light in human skin. Camouse MM, Domingo DS, Swain FR, Conrad EP, Matsui MS, Maes D, Declercq L, Cooper KD, Stevens SR, Baron ED. Exp Dermatol. 2009 Jun;18(6):522-6. doi: 10.1111/j.1600-0625.2008.00818.x. PMID: 19492999
Protective effect of white tea extract against acute oxidative injury caused by adriamycin in different tissues. Espinosa C, López-Jiménez JÁ, Cabrera L, Larqué E, Almajano MP, Arnao MB, Zamora S, Pérez-Llamas F. Food Chem. 2012 Oct 15;134(4):1780-5. doi: 10.1016/j.foodchem.2012.03.083. Epub 2012 Mar 29. PMID: 23442621
[Studies on tea and health]. Han C. Wei Sheng Yan Jiu. 2011 Nov;40(6):802-5. Review. Chinese. PMID: 22279681
(c) Juan M García. 2012.
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Del latin: in-tui = "en" lo "de ti"